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Image Search Results
Journal: Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents
Article Title: Combination with a FtsZ inhibitor potentiates the in vivo efficacy of oxacillin against methicillin-resistant Staphylococcus aureus
doi: 10.1007/s00044-022-02960-5
Figure Lengend Snippet: Impact of TXA707 on the activity of oxacillin against clinical isolates of MRSA, VRSA, VISA, and LRSA
Article Snippet: Bacterial isolates and antibacterial agents Clinical isolates of MRSA, VISA, VRSA and
Techniques: Activity Assay
Journal: Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents
Article Title: Combination with a FtsZ inhibitor potentiates the in vivo efficacy of oxacillin against methicillin-resistant Staphylococcus aureus
doi: 10.1007/s00044-022-02960-5
Figure Lengend Snippet: Time-kill curves for MRSA NRS705 (USA100) (A), MRSA NRS643 (USA300) (B), VRSA VRS5 (C), VISA NRS27 (D), and LRSA NRS127 (E) showing the potentiation of oxacillin activity resulting from the synergistic combination with TXA707. Bacteria were treated with DMSO vehicle, oxacillin alone at 2 μg/mL (0.004x–0.03x MIC), TXA707 alone at 0.5 μg/mL (0.5x MIC), or a combination of TXA707 at 0.5 μg/mL and oxacillin at a range of concentrations from 0.125–2 μg/mL
Article Snippet: Bacterial isolates and antibacterial agents Clinical isolates of MRSA, VISA, VRSA and
Techniques: Activity Assay, Bacteria
Journal: Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents
Article Title: Combination with a FtsZ inhibitor potentiates the in vivo efficacy of oxacillin against methicillin-resistant Staphylococcus aureus
doi: 10.1007/s00044-022-02960-5
Figure Lengend Snippet: Resistance frequencies of representative MRSA, VISA, VRSA, and LRSA isolates to TXA707 alone or in combination with oxacillin
Article Snippet: Bacterial isolates and antibacterial agents Clinical isolates of MRSA, VISA, VRSA and
Techniques: